Gangrene is an American hip hop and record production duo from Los Angeles, California. The group consists of rappers/record producers The Alchemist and Oh No. The two previously had lengthy solo careers and worked with mutual artists, but were not acquainted until they met at a show headlined by Dilated Peoples member Evidence. The two connected and proposed a collaborative project. Gangrene have released four studio albums, two EPs and a collaborative EP with Roc Marciano.
In 2013, Gangrene, Tangerine Dream and Woody Jackson scored and composed the original score for the video game Grand Theft Auto V by Rockstar Games.